Since the 1st Variant Effect Prediction Training Course (VEPTC) in 2016, Global Variome has held this annual training course as part of its mission to build capacity in the practice of responsible genomics and contribute to improving global health outcomes. Global Variome along with the Human Genome Variation Society (HGVS) have now merged with The Human Genome Organisation (HUGO) International who will continue to offer educational courses and conferences to advance genome science and technology.